Special Cases - When It Is Trickier
đż This Is My Happy Space â The âComplexâ Patients
I hate that wordâcomplex.
But I use it here with care, because what it really means to me is time.
A patient I can sit with for an hour or two (yes, I know thatâs a luxury), go deep, ask the right questions, and actually understand.
Over time, Iâve realised that many of these so-called âcomplexâ casesâthe ones other clinicians might quietly call âheart sinkâ patientsâare actually special hormonal stories. Not always obvious. Not always linear. But always worth it.
Because when we consider hormones as part of the picture, something shifts.
People feel seen. Patterns emerge. And sometimesâyes, reallyâsymptoms improve.
These are the patients who have taught me more than I could ever have imagined.
And theyâve reminded me that dreams do come true.
Especially when we stop assuming and start listening.
But, this is where I learnt how I practice.
Where Iâve been challenged.
Where the science finally makes sense.
Where Iâve seen textbook theory replaced with real human livesâand why that matters more than anything.
Itâs in the validation of an autistic woman who felt like she was losing her mind every three weeksâuntil she removed her estrogen patch and suddenly felt relief. (It turns out those patches peak and reach steady state at around three weeks.)
Itâs in the post-surgical menopause patient who was on high-dose estrogen, feeling betterâbut not quite right. And we realised: patches can bring big peaks and troughs.
Itâs in the 20-year-old with POI who bled continuously and couldnât tolerate progestins but was desperate for anything that might stop the bleeding. Or the other 20-year-old who just wanted to feel like her friends, and the pill gave her that.
Itâs in the woman with a history of breast cancer, spiralling into suicidal depression, who had tried everything else. Starting MHT gave her life back. Her husband said he had her back. She became a present, vibrant grandmother again, spending summers with her moko.
Itâs in the 35-year-old whoâd been on Depot Provera for a decadeâhypoestrogenic, with chronic dry eyes, vaginal dryness, multiple specialists involvedâand no one had considered low estrogen.
Itâs in the 24-year-old with endometriosis on 9-weekly Depo injections. Her estradiol levels seemed âfine,â but symptoms told a different story: vulval fissures, thin red vaginal walls, signs of atrophy. She needed local estrogen and topical steroidsânot just disease suppression, but restoration.
Itâs in the 59-year-old grandma who started HRT for âtypicalâ symptoms, felt amazing for 6 months, and then stopped. But now, she still gets up and down off the floor to play with her grandchildren. Thatâs her win.
Every patient teaches me something. And what every one of them has shown me is that when I go back to the foundationsâlisten to the person, understand the whÄnau, and map the hormonal timelineâwe find solutions. We make educated guesses that arenât stabs in the dark, but deeply informed starting points. Sometimes itâs surprising. Like the women who become more anxious or develop insomnia with progesterone, even though 98% of others feel calm and sleepy. Hormones are complicatedâand thatâs okay.
Because patients know their bodies. My role as a doctor is to ask the right questions, hear what you already know, and bring science and skill into the room so we can figure it outâtogether. Especially in perimenopause, weâre working with a shifting baseline. The target moves. And sometimes we go back to the drawing board. Thatâs not failureâitâs part of the process.
One of the patterns I often see: someone starts MHT and feels incredible. Then, it fades. Maybe thereâs receptor saturation. But when the hormones drop again, it hits harder. That fall feels further because you remember what it was like to feel well. But hereâs the thing: now you have reference points. You know what better felt like. And that makes it easier to recover, adjust, and bounce back. Eventually, when you stumble, youâll recognise the signs earlier. Youâll advocate for yourself. And if you fall againâbecause sometimes life makes sure we doâyouâll know itâs not forever.
And most importantly, youâll know itâs not just hormones.
But when it is?
Weâll figure it out. Together.
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